Bayer K9 Advantix II Reviews: Flea and Tick Control Treatment for Dogs

Did you know fleas and ticks are not just annoying for pets but can also cause them some amount of harm. Ticks are ectoparasites that hides quite well within the fur of your dog.

You will never get to see them unless you actually part the coat of your dog and look deeper. These are blood sucking parasites and attach themselves to your dog by inserting their fangs into the skin of your dog.

The reason for fear lies is what ticks can really do to your dog. There are certain species of female ticks that can cause a rare type of paralysis in dogs as they produce a toxin while feeding.

Ticks are also quite capable of causing several infections or medical ailment to your dog and the most common is Lyme disease and Rocky Mountain spotted fever.

On the other hand, there is the dog flea also known as Ctenocephalides canis and it can live on both dogs and cats. Being a parasite, they also feed on the blood and can deliver an astonishing 4000 eggs on your dog's fur.

Flea infestations can cause mild to severe itching and even cause skin infections including anemia and hair loss. They are also known to transmit tapeworms.

This is where Bayer K9 Advantix II comes to the rescue!

What is K9 Advantix II?

Bayer K9 Advantix II is a topical prevention and treatment of fleas, ticks, flies, and mosquitoes on dogs as well as puppies that are 7 weeks of age or older.

The K9 Advantix II is being manufactured and marketed by BayerDVM that supports pet health.

They manufacture a variety of products for cats, dogs, and horses and these include flea and tick control treatment for animals or pets.

Bayer AG, the parent company is a German multinational pharmaceutical, chemical, and life sciences company that was founded 153 years ago.

It comes with a great reputation and Bayer Animal Health division manufactures products that protect millions of food animals.

k9 Advantix II Review

K9 Advantix Features

  • Kills fleas, ticks and mosquitoes through contact, no biting requied
  • Kills all life stages and prevents fleas on treated dogs from re-infesting
  • Veterinarian Recommended
  • Convenient, easy to apply monthly topical for use on dogs or puppies 7 weeks of age or older
  • Also kills lice and repels biting flies
  • Repels and kills ticks before they can attach and mosquitoes before they can bite
  • Kills adult fleas, eggs and larvae

What K9 Advantix II does for dogs?

The Bayer K9 Advantix II flea and tick control treatment for dogs being reviewed here is focused at large dogs weighing between 21 and 55lbs. This doesn't mean this product is not available for small dogs.

K9 Advantix II is available for dogs weighing from 4-55lbs and even more. This is a topical medication, which means it can be applied directly onto the skin of your dog.

  • Safety
  • storage
  • ingredients

Bayer K9 Advantix II is a powerful flea and tick control treatment for dogs and it is quite safe to use for large dogs that weigh 21-55lbs. It is also a highly recommended product by veterinarians.

The only known side effects include symptoms of skin irritation like scratching, and redness. Gastrointestinal problems like diarrhea and vomiting have also been reported.


The medication should be kept out of reach for children as it can be harmful to them

Benefits of using this product

The salient benefit of using Bayer K9 Advantix II is that it repels and kills all life stages of fleas as well as Deer ticks, American dog ticks, and Brown dog ticks and its effectiveness is there for almost 4 weeks.

Remember to wash your dog flea control shampoos before applying this medicine

How to use K9 Advantix II?

K9 Advantix II is a topical application that has to be applied once a day for 30 days. The process of application is as follows:

Step#1: Remove the applicator tube from the package

Step#2: Use scissors to peel down the foil

Step#3: Hold the applicator tube in upright position and pull the cap off the tube.

Step#4: Twist the cap around and place the other end of the cap at the opening of the tube.

Step#5: Twist the cap to break the seal of the tube and then remove the cap.

Step#6: Part the hair of your dog between his/her shoulder blades.

Step#4: Gently place the applicator tip right above the skin of your dog and squeeze.

Note: Ensure your dog is in a standing position and apply the entire contents of a single applicator in a single spot only. You need to apply it on the skin and not hair.

When used with flea collar or flea shampoo this tick repellent works much effectively than normal.

Pros and Cons of K9 Advantix:

Since, K9 Advantix II is an effective insecticide or pesticide, it has its pros and cons as well. Let’s take a quick look at them.

Things we liked

  • It repels and kills ticks including Deer ticks (causes Lyme disease), Brown dog ticks(cause Ehrlichiosis), American dog ticks (causes Rocky Mountain Spotted Fever), and Lone Star ticks (causes Ehrlichiosis).
  • Pyriproxyfen IGR in K9 Advantix II repels and kills flea and disrupts all stages of a flea life cycle.
  • It is easily available as it is an Over-the-counter flea and tick control product.
  • It kills fleas within 12 hours and continues to prevent any infestation for a month.
  • It provides a 5-way protection to your dog against fleas, ticks, mosquitoes, chewing lice, and biting flies.
  • It is water resistant and easy to administer using an applicator that spreads the medicine directly into the dog’s coat.

Things we didn't Like

  • It is a topical medication that can cause temporary eye injury and is harmful to humans if absorbed through the skin.
  • K9 Advantix II is highly toxic to aquatic organisms including fish and invertebrates.

K9 Advantix Vs Frontline

There are several different products available in the market that promises to be highly effective in killing fleas as well as ticks. K9 Advantix is one of the best and hence it would be appropriate to take look at a head-to-head comparison of two top products

K9 Advantix






OTC (Over the Counter)

OTC (Over the Counter)


Imidacloprid, Permethrin, and Pyriproxyfen IGR

fipronil and (S)-methoprene


100% effectiveness against adult fleas, ticks, chewing lice, mosquitoes, and lice.

100% effectiveness against adult fleas, ticks, and chewing lice.


Is available with 6 applicators

Is available with 6 applicators

Our Rating

k9 Advantix II Review
Frontline Plus Reviews

Final Verdict on K9 Advantix II

Yes, there are several top flea and tick control treatment for dogs available out there in the market but the K9 Advantix II by Bayer does stand out of the crowd. It is not only a highly effective treatment but is easy to apply.

k9 Advantix II Review
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